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The Regulation of Aging and Longevity: A New and Complex Role of p53

p53 plays a critical role in tumor suppression. As a transcription factor, in response to stress signals, p53 regulates its target genes and initiates stress responses, including cell cycle arrest, apoptosis, and/or senescence, to exert its function in tumor suppression. Emerging evidence has sugges...

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書目詳細資料
Main Authors: Feng, Zhaohui, Lin, Meihua, Wu, Rui
格式: Artigo
語言:Inglês
出版: SAGE Publications 2011
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135645/
https://ncbi.nlm.nih.gov/pubmed/21779512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911410223
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