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The Regulation of Aging and Longevity: A New and Complex Role of p53
p53 plays a critical role in tumor suppression. As a transcription factor, in response to stress signals, p53 regulates its target genes and initiates stress responses, including cell cycle arrest, apoptosis, and/or senescence, to exert its function in tumor suppression. Emerging evidence has sugges...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135645/ https://ncbi.nlm.nih.gov/pubmed/21779512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911410223 |
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