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Out-of-Frame T Cell Receptor Beta Transcripts Are Eliminated by Multiple Pathways In Vivo

Non-productive antigen receptor genes with frame shifts generated during the assembly of these genes are found in many mature lymphocytes. Transcripts from these genes have premature termination codons (PTCs) and could encode truncated proteins if they are not either inactivated or destroyed by nons...

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Autors principals: Mahowald, Grace K., Mahowald, Michael A., Moon, Clara, Khor, Bernard, Sleckman, Barry P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135592/
https://ncbi.nlm.nih.gov/pubmed/21765899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021627
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