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Out-of-Frame T Cell Receptor Beta Transcripts Are Eliminated by Multiple Pathways In Vivo

Non-productive antigen receptor genes with frame shifts generated during the assembly of these genes are found in many mature lymphocytes. Transcripts from these genes have premature termination codons (PTCs) and could encode truncated proteins if they are not either inactivated or destroyed by nons...

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Détails bibliographiques
Auteurs principaux: Mahowald, Grace K., Mahowald, Michael A., Moon, Clara, Khor, Bernard, Sleckman, Barry P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135592/
https://ncbi.nlm.nih.gov/pubmed/21765899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021627
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