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Out-of-Frame T Cell Receptor Beta Transcripts Are Eliminated by Multiple Pathways In Vivo

Non-productive antigen receptor genes with frame shifts generated during the assembly of these genes are found in many mature lymphocytes. Transcripts from these genes have premature termination codons (PTCs) and could encode truncated proteins if they are not either inactivated or destroyed by nons...

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Bibliografische gegevens
Hoofdauteurs: Mahowald, Grace K., Mahowald, Michael A., Moon, Clara, Khor, Bernard, Sleckman, Barry P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135592/
https://ncbi.nlm.nih.gov/pubmed/21765899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021627
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