Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44

Tissue fibrosis is a major cause of morbidity, and idiopathic pulmonary fibrosis (IPF) is a terminal illness characterized by unremitting matrix deposition in the lung. The mechanisms that control progressive fibrosis are unknown. Myofibroblasts accumulate at sites of tissue remodeling and produce e...

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Bibliographic Details
Main Authors: Li, Yuejuan, Jiang, Dianhua, Liang, Jiurong, Meltzer, Eric B., Gray, Alice, Miura, Riu, Wogensen, Lise, Yamaguchi, Yu, Noble, Paul W.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135364/
https://ncbi.nlm.nih.gov/pubmed/21708929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102510
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