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Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44
Tissue fibrosis is a major cause of morbidity, and idiopathic pulmonary fibrosis (IPF) is a terminal illness characterized by unremitting matrix deposition in the lung. The mechanisms that control progressive fibrosis are unknown. Myofibroblasts accumulate at sites of tissue remodeling and produce e...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135364/ https://ncbi.nlm.nih.gov/pubmed/21708929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102510 |
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