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Transcriptional regulation of the Th17 immune response by IKKα
Th17 cells are a subset of T cells that play crucial roles in the pathogenesis of many inflammatory diseases. We report here the identification of IKKα (inhibitor of NF-κB kinase-α) as a key transcriptional regulator of the Th17 lineage. T cells expressing a nonactivatable form of IKKα were signific...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135338/ https://ncbi.nlm.nih.gov/pubmed/21402739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091346 |
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