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The transcription factor Th-POK negatively regulates Th17 differentiation in Vα14i NKT cells
The majority of mouse Vα14 invariant natural killer T (Vα14i NKT) cells produce several cytokines, including IFNγ and IL-4, very rapidly after activation. A subset of these cells, known as NKT17 cells, however, differentiates in the thymus to preferentially produce IL-17. Here, we show that the tran...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3512232/ https://ncbi.nlm.nih.gov/pubmed/23034280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-406280 |
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