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Ionic mechanisms and Ca(2+) dynamics underlying the glucose response of pancreatic β cells: a simulation study

To clarify the mechanisms underlying the pancreatic β-cell response to varying glucose concentrations ([G]), electrophysiological findings were integrated into a mathematical cell model. The Ca(2+) dynamics of the endoplasmic reticulum (ER) were also improved. The model was validated by demonstratin...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Cha, Chae Young, Nakamura, Yasuhiko, Himeno, Yukiko, Wang, JianWu, Fujimoto, Shinpei, Inagaki, Nobuya, Earm, Yung E, Noma, Akinori
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135323/
https://ncbi.nlm.nih.gov/pubmed/21708953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110611
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