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A Model of Na(+)/H(+) Exchanger and Its Central Role in Regulation of pH and Na(+) in Cardiac Myocytes

A new kinetic model of the Na(+)/H(+) exchanger (NHE) was developed by fitting a variety of major experimental findings, such as ion-dependencies, forward/reverse mode, and the turnover rate. The role of NHE in ion homeostasis was examined by implementing the NHE model in a minimum cell model includ...

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Detalhes bibliográficos
Main Authors: Cha, Chae Young, Oka, Chiaki, Earm, Yung E., Wakabayashi, Shigeo, Noma, Akinori
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776256/
https://ncbi.nlm.nih.gov/pubmed/19917220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.053
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