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Experimental Generation and Computational Modeling of Intracellular pH Gradients in Cardiac Myocytes
It is often assumed that pH(i) is spatially uniform within cells. A double-barreled microperfusion system was used to apply solutions of weak acid (acetic acid, CO(2)) or base (ammonia) to localized regions of an isolated ventricular myocyte (guinea pig). A stable, longitudinal pH(i) gradient (up to...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Biophysical Society
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1305395/ https://ncbi.nlm.nih.gov/pubmed/15653720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051391 |
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