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Ionic mechanisms and Ca(2+) dynamics underlying the glucose response of pancreatic β cells: a simulation study
To clarify the mechanisms underlying the pancreatic β-cell response to varying glucose concentrations ([G]), electrophysiological findings were integrated into a mathematical cell model. The Ca(2+) dynamics of the endoplasmic reticulum (ER) were also improved. The model was validated by demonstratin...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135323/ https://ncbi.nlm.nih.gov/pubmed/21708953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110611 |
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