Chaperone Hsp27 Modulates AUF1 Proteolysis and AU-Rich Element-Mediated mRNA Degradation

AUF1 is an AU-rich element (ARE)-binding protein that recruits translation initiation factors, molecular chaperones, and mRNA degradation enzymes to the ARE for mRNA destruction. We recently found chaperone Hsp27 to be an AUF1-associated ARE-binding protein required for tumor necrosis factor alpha (...

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Bibliografiske detaljer
Main Authors: Knapinska, Anna M., Gratacós, Frances M., Krause, Christopher D., Hernandez, Kristina, Jensen, Amber G., Bradley, Jacquelyn J., Wu, Xiangyue, Pestka, Sidney, Brewer, Gary
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135302/
https://ncbi.nlm.nih.gov/pubmed/21245386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00907-10
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