Regulation of PIDD auto-proteolysis and activity by the molecular chaperone Hsp90

In response to DNA damage, p53-induced protein with a death domain (PIDD) forms a complex called the PIDDosome, which either consists of PIDD, RIP-associated protein with a death domain and caspase-2, forming a platform for the activation of caspase-2, or contains PIDD, RIP1 and NEMO, important for...

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Bibliografiske detaljer
Main Authors: Tinel, A, Eckert, M J, Logette, E, Lippens, S, Janssens, S, Jaccard, B, Quadroni, M, Tschopp, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131991/
https://ncbi.nlm.nih.gov/pubmed/20966961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.124
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