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Regulation of PIDD auto-proteolysis and activity by the molecular chaperone Hsp90
In response to DNA damage, p53-induced protein with a death domain (PIDD) forms a complex called the PIDDosome, which either consists of PIDD, RIP-associated protein with a death domain and caspase-2, forming a platform for the activation of caspase-2, or contains PIDD, RIP1 and NEMO, important for...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131991/ https://ncbi.nlm.nih.gov/pubmed/20966961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.124 |
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