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Inhibitory Phosphorylation of Cyclin-Dependent Kinase 1 as a Compensatory Mechanism for Mitosis Exit

The current paradigm states that exit from mitosis is triggered by the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C) acting in concert with an activator called CDC20. While this has been well established for a number of systems, the evidence of a critical role of CDC20 in somatic cel...

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Detalhes bibliográficos
Main Authors: Chow, Jeremy P. H., Poon, Randy Y. C., Ma, Hoi Tang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135293/
https://ncbi.nlm.nih.gov/pubmed/21262764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00891-10
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