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Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions

Little is known about how combinations of histone marks are interpreted at the level of nucleosomes. The second PHD finger of human BPTF is known to specifically recognize histone H3 when methylated on lysine 4 (H3K4me2/3); here we examine how additional heterotypic modifications influence BPTF bind...

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Detalhes bibliográficos
Main Authors: Ruthenburg, Alexander J., Li, Haitao, Milne, Thomas A., Dewell, Scott, McGinty, Robert K., Yuen, Melanie, Ueberheide, Beatrix, Dou, Yali, Muir, Tom W., Patel, Dinshaw J., Allis, C. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135172/
https://ncbi.nlm.nih.gov/pubmed/21596426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.03.053
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