Protection against Autoimmune Diabetes by Silkworm-Produced GFP-Tagged CTB-Insulin Fusion Protein

In animals, oral administration of the cholera toxin B (CTB) subunit conjugated to the autoantigen insulin enhances the specific immune-unresponsive state. This is called oral tolerance and is capable of suppressing autoimmune type 1 diabetes (T1D). However, the process by which the CTB-insulin (CTB...

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Bibliographic Details
Main Authors: Meng, Qiaohong, Wang, Wenfeng, Shi, Xiaowen, Jin, Yongfeng, Zhang, Yaozhou
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135140/
https://ncbi.nlm.nih.gov/pubmed/21765853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/831704
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