The Pleiotropic Actions of Adiponectin are Initiated via Receptor-Mediated Activation of Ceramidase Activity

The adipocyte-derived secretory factor adiponectin promotes insulin sensitivity, decreases inflammation and promotes cell survival. To date, no unifying mechanism explains how adiponectin can exert such a variety of beneficial systemic effects. Here, we show that adiponectin potently stimulates a ce...

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Detalhes bibliográficos
Main Authors: Holland, William L., Miller, Russell A., Wang, Zhao V., Sun, Kai, Barth, Brian M., Bui, Hai H., Davis, Kathryn E., Bikman, Benjamin T., Halberg, Nils, Rutkowski, Joseph M., Wade, Mark R., Tenorio, Vincent M., Kuo, Ming-Shang, Brozinick, Joseph T., Zhang, Bei B., Birnbaum, Morris J., Summers, Scott A., Scherer, Philipp E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134999/
https://ncbi.nlm.nih.gov/pubmed/21186369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2277
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