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Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis

OBJECTIVE: Adiponectin and the signaling induced by its cognate receptors, AdipoR1 and AdipoR2, have garnered attention for their ability to promote insulin sensitivity and oppose steatosis. Activation of these receptors promotes the deacylation of ceramide, a lipid metabolite that appears to play a...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Holland, William L., Xia, Jonathan Y., Johnson, Joshua A., Sun, Kai, Pearson, Mackenzie J., Sharma, Ankit X., Quittner-Strom, Ezekiel, Tippetts, Trevor S., Gordillo, Ruth, Scherer, Philipp E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323887/
https://ncbi.nlm.nih.gov/pubmed/28271033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.01.002
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