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Structural insights into adiponectin receptors suggest ceramidase activity
Adiponectin receptors (ADIPORs) are integral membrane proteins controlling glucose and lipid metabolism by mediating, at least in part, a cellular ceramidase activity1 which catalyzes the hydrolysis of ceramide to produce sphingosine and a free fatty acid (FFA). The recent crystal structures of the...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5595237/ https://ncbi.nlm.nih.gov/pubmed/28329765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21714 |
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