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The structure of neurexin 1α reveals features promoting a role as synaptic organizer

α-Neurexins are essential synaptic adhesion molecules implicated in autism spectrum disorder and schizophrenia. The α-neurexin extracellular domain consists of 6 LNS domains interspersed by 3 EGF-like repeats and interacts with many different proteins in the synaptic cleft. To understand how α-neure...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, Fang, Venugopal, Vandavasi, Murray, Beverly, Rudenko, Gabby
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134934/
https://ncbi.nlm.nih.gov/pubmed/21620716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.03.012
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