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The structure of neurexin 1α reveals features promoting a role as synaptic organizer
α-Neurexins are essential synaptic adhesion molecules implicated in autism spectrum disorder and schizophrenia. The α-neurexin extracellular domain consists of 6 LNS domains interspersed by 3 EGF-like repeats and interacts with many different proteins in the synaptic cleft. To understand how α-neure...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3134934/ https://ncbi.nlm.nih.gov/pubmed/21620716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.03.012 |
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