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Interplay between hevin, SPARC, and MDGAs: modulators of neurexin-neuroligin trans-synaptic bridges.
Hevin is secreted by astrocytes and its synaptogenic effects are antagonized by related protein, SPARC. Hevin stabilizes neurexin-neuroligin trans-synaptic bridges in vivo. A third protein, membrane-tethered MDGA, blocks these bridges. Here, we reveal the molecular underpinnings of a regulatory netw...
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| Publicado no: | Structure |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8254758/ https://ncbi.nlm.nih.gov/pubmed/33535026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2021.01.003 |
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