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Imaging activity-dependent regulation of neurexin-neuroligin interactions using trans-synaptic enzymatic biotinylation

The functions of trans-synaptic adhesion molecules such as neurexin and neuroligin have been difficult to study due to the lack of methods to directly detect their binding in living neurons. Here, we use Biotin Labeling of INtercellular Contacts (BLINC), a method for imaging protein interactions bas...

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Detalhes bibliográficos
Main Authors: Thyagarajan, Amar, Ting, Alice Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966532/
https://ncbi.nlm.nih.gov/pubmed/20933261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.09.025
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