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The Role of Platelet Factor 4 in Radiation-Induced Thrombocytopenia

PURPOSE: Factors affecting the severity of radiation-induced thrombocytopenia (RIT) are not well-described. We address whether PF4 (a negative paracrine for megakaryopoiesis) affects platelet recovery post-radiation. MATERIALS AND METHODS: Using conditioned media from irradiated bone marrow (BM) cel...

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Main Authors: Lambert, Michele P., Xiao, Liqing, Nguyen, Yvonne, Kowalska, Anna M., Poncz, Mortimer
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134787/
https://ncbi.nlm.nih.gov/pubmed/21740995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2011.03.039
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