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Calpain and PARP Activation during Photoreceptor Cell Death in P23H and S334ter Rhodopsin Mutant Rats

Retinitis pigmentosa (RP) is a heterogeneous group of inherited neurodegenerative diseases affecting photoreceptors and causing blindness. Many human cases are caused by mutations in the rhodopsin gene. An important question regarding RP pathology is whether different genetic defects trigger the sam...

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Main Authors: Kaur, Jasvir, Mencl, Stine, Sahaboglu, Ayse, Farinelli, Pietro, van Veen, Theo, Zrenner, Eberhart, Ekström, Per, Paquet-Durand, François, Arango-Gonzalez, Blanca
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134478/
https://ncbi.nlm.nih.gov/pubmed/21765948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022181
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