Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats.

Retinitis pigmentosa (RP) is a heterogeneous group of inherited neurodegenerative diseases affecting photoreceptors and causing blindness. Many human cases are caused by mutations in the rhodopsin gene. An important question regarding RP pathology is whether different genetic defects trigger the sam...

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Huvudupphovsmän: Jasvir Kaur, Stine Mencl, Ayse Sahaboglu, Pietro Farinelli, Theo van Veen, Eberhart Zrenner, Per Ekström, François Paquet-Durand, Blanca Arango-Gonzalez
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science (PLoS) 2011-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC3134478?pdf=render
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