Temporal progression of PARP activity in the Prph2 mutant rd2 mouse: Neuroprotective effects of the PARP inhibitor PJ34

Peripherin (peripherin/rds) is a membrane-associated protein that plays a critical role in the morphogenesis of rod and cone photoreceptor outer segments. Mutations in the corresponding PRPH2 gene cause different types of retinal dystrophies characterized by a loss of photoreceptors. Over activation...

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Udgivet i:PLoS One
Main Authors: Sahaboglu, Ayse, Sharif, Alaa, Feng, Lili, Secer, Enver, Zrenner, Eberhart, Paquet-Durand, François
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517001/
https://ncbi.nlm.nih.gov/pubmed/28723922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181374
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