Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survival

BACKGROUND: Raf-1 kinase inhibitor protein (RKIP) has been reported to negatively regulate signal kinases of major survival pathways. RKIP activity is modulated in part by phosphorylation on Serine 153 by protein kinase C, which leads to dissociation of RKIP from Raf-1. RKIP expression is low in man...

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Bibliografske podrobnosti
Main Authors: Huerta-Yepez, Sara, Yoon, Nam K, Hernandez-Cueto, Angeles, Mah, Vei, Rivera-Pazos, Clara M, Chatterjee, Devasis, Vega, Mario I, Maresh, Erin L, Horvath, Steve, Chia, David, Bonavida, Benjamin, Goodglick, Lee
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134426/
https://ncbi.nlm.nih.gov/pubmed/21689459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-259
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