Ribonucleotide Reductase Subunit M2 Predicts Survival in Subgroups of Patients with Non-Small Cell Lung Carcinoma: Effects of Gender and Smoking Status

BACKGROUND: Ribonucleotide reductase catalyzes the conversion of ribonucleotide diphosphates to deoxyribonucleotide diphosphates. The functional enzyme consists of two subunits - one large (RRM1) and one small (RRM2 or RRM2b) subunit. Expression levels of each subunit have been implicated in prognos...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Mah, Vei, Alavi, Mohammad, Márquez-Garbán, Diana C., Maresh, Erin L., Kim, Sara R., Horvath, Steve, Bagryanova, Lora, Huerta-Yepez, Sara, Chia, David, Pietras, Richard, Goodglick, Lee
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441434/
https://ncbi.nlm.nih.gov/pubmed/26001082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127600
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