Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survival

BACKGROUND: Raf-1 kinase inhibitor protein (RKIP) has been reported to negatively regulate signal kinases of major survival pathways. RKIP activity is modulated in part by phosphorylation on Serine 153 by protein kinase C, which leads to dissociation of RKIP from Raf-1. RKIP expression is low in man...

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Bibliografiska uppgifter
Huvudupphovsmän: Huerta-Yepez, Sara, Yoon, Nam K, Hernandez-Cueto, Angeles, Mah, Vei, Rivera-Pazos, Clara M, Chatterjee, Devasis, Vega, Mario I, Maresh, Erin L, Horvath, Steve, Chia, David, Bonavida, Benjamin, Goodglick, Lee
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134426/
https://ncbi.nlm.nih.gov/pubmed/21689459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-259
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