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Systemic activation of K-ras rapidly induces gastric hyperplasia and metaplasia in mice

Mouse models with conditional activation of K-ras (K-ras(G12D)) are used widely to investigate the role of oncogenic K-ras in a tissue-specific manner. However, the effect of ubiquitous activation of K-ras in adult mice has not been well studied. Herein, we report that systemic activation of K-ras i...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Matkar, Smita S, Durham, Amy, Brice, Angela, Wang, Timothy C, Rustgi, Anil K, Hua, Xianxin
פורמט: Artigo
שפה:Inglês
יצא לאור: e-Century Publishing Corporation 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134228/
https://ncbi.nlm.nih.gov/pubmed/21761008
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