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A Facile Approach to the Synthesis of 3,4-Disubstituted-2-Aminothiazolium Derivatives through the Use of A “Volatilizable” Support

A facile solid-phase synthetic approach to the synthesis of 3,4-disubstituted-2-aminothiazolium derivatives was reported. Functionalized aminomethylphenyl silica gel was used as a “volatilizable” support. The products were cleaved with 10% HF and were obtained in high yields and purities.

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Hlavní autoři: Li, Yangmei, Giulianotti, Marc, Houghten, Richard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133972/
https://ncbi.nlm.nih.gov/pubmed/21765557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.08.026
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