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An HSV vector system for selection of ligand-gated ion channel modulators
Pathological alterations of ion channel activity result from changes in modulatory mechanisms governing receptor biology. Here we describe a conditional herpes simplex virus (HSV) replication–based strategy to discover channel modulators whereby inhibition of agonist-induced channel activation by a...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133941/ https://ncbi.nlm.nih.gov/pubmed/17676048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth1077 |
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