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Safety and biodistribution studies of an HSV multigene vector following intracranial delivery to non-human primates

Malignant glioma is a fatal human cancer in which surgery, chemo- and radiation therapies are ineffective. Therapeutic gene transfer used in combination with current treatment methods may augment their effectiveness with improved clinical outcome. We have shown that NUREL-C2, a replication-defective...

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Bibliografische gegevens
Hoofdauteurs: Wolfe, D, Niranjan, A, Trichel, A, Wiley, C, Ozuer, A, Kanal, E, Kondziolka, D, Krisky, D, Goss, J, DeLuca, N, Murphey-Corb, M, Glorioso, JC
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449743/
https://ncbi.nlm.nih.gov/pubmed/15306839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3302336
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