An HSV vector system for selection of ligand-gated ion channel modulators

Pathological alterations of ion channel activity result from changes in modulatory mechanisms governing receptor biology. Here we describe a conditional herpes simplex virus (HSV) replication–based strategy to discover channel modulators whereby inhibition of agonist-induced channel activation by a...

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Hlavní autoři: Srinivasan, Rahul, Huang, Shaohua, Chaudhry, Suchita, Sculptoreanu, Adrian, Krisky, David, Cascio, Michael, Friedman, Peter A, de Groat, William C, Wolfe, Darren, Glorioso, Joseph C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133941/
https://ncbi.nlm.nih.gov/pubmed/17676048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth1077
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