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Dual blockade of the EGFR and COX-2 pathways: A phase II trial of cetuximab and celecoxib in patients with chemotherapy refractory metastatic colorectal cancer
OBJECTIVES: The epidermal growth factor receptor and cyclooxygenase-2 pathways play key and often complementary roles in the pathogenesis of colorectal cancer (CRC). This study explores the clinical and biological effects of combined blockade of these pathways METHODS: Cetuximab-naive patients with...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133812/ https://ncbi.nlm.nih.gov/pubmed/21217396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COC.0b013e3181fe46a1 |
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