ADAM-10-Mediated N-Cadherin Cleavage Is Protein Kinase C-α Dependent and Promotes Glioblastoma Cell Migration

MMPs (matrix metalloproteinases) and the related “a disintegrin and metalloproteinases” (ADAMs) promote tumorigenesis by cleaving extracellular matrix and protein substrates, including N-cadherin. Although N-cadherin is thought to regulate cell adhesion, migration, and invasion, its role has not bee...

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Bibliografiska uppgifter
Huvudupphovsmän: Kohutek, Zachary A., diPierro, Charles G., Redpath, Gerard T., Hussaini, Isa M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2009
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133728/
https://ncbi.nlm.nih.gov/pubmed/19357285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5126-08.2009
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