An Extensive Invasive Intracranial Human Glioblastoma Xenograft Model : Role of High Level Matrix Metalloproteinase 9

The lack of an intracranial human glioma model that recapitulates the extensive invasive and hypervascular features of glioblastoma (GBM) is a major hurdle for testing novel therapeutic approaches against GBM and studying the mechanism of GBM invasive growth. We characterized a high matrix metallopr...

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Main Authors: Zhao, Yunge, Xiao, Aizhen, diPierro, Charles G., Carpenter, Joan E., Abdel-Fattah, Rana, Redpath, Gerard T., Lopes, Maria-Beatriz S., Hussaini, Isa M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877863/
https://ncbi.nlm.nih.gov/pubmed/20413683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090571
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