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Protein Kinase C-α–Mediated Regulation of Low-Density Lipoprotein Receptor–Related Protein and Urokinase Increases Astrocytoma Invasion

Aggressive and infiltrative invasion is one of the hallmarks of glioblastoma. Low-density lipoprotein receptor–related protein (LRP) is expressed by glioblastoma, but the role of this receptor in astrocytic tumor invasion remains poorly understood. We show that activation of protein kinase C-α (PKC-...

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Detalhes bibliográficos
Main Authors: Amos, Samson, Mut, Melike, diPierro, Charles G., Carpenter, Joan E., Xiao, Aizhen, Kohutek, Zachary A., Redpath, Gerard T., Zhao, Yunge, Wang, Jiahu, Shaffrey, Mark E., Hussaini, Isa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386949/
https://ncbi.nlm.nih.gov/pubmed/17974965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-0030
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