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Stat3 Phosphorylation Mediates Resistance of Primary Human T Cells to Regulatory T Cell Suppression
Human autoimmune diseases are characterized by systemic T cell dysfunction, resulting in chronically activated Th1 and Th17 cells that are inadequately suppressed by regulatory T cells (Tregs). IL-6, which is overexpressed in tissue and serum of patients with autoimmune diseases, inhibits human Treg...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133678/ https://ncbi.nlm.nih.gov/pubmed/21307288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001455 |
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