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IL-6 Signaling in Psoriasis Prevents Immune Suppression by Regulatory T Cells
T memory/effector cells (Tmem/eff) isolated from psoriatic patients are chronically activated and poorly suppressed by regulatory T cells (Treg). The proinflammatory cytokine IL-6, which signals through Stat3, allows escape of Tmem/eff cells from Treg-mediated suppression in a murine system. We show...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903207/ https://ncbi.nlm.nih.gov/pubmed/19648274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803721 |
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