Caricamento...

Ptf1a and Nkx6 transcription factors function as antagonistic lineage determinants in multipotent pancreatic progenitors

The molecular mechanisms that underlie cell lineage diversification of multipotent progenitors in the pancreas are virtually unknown. Here, we show that the early fate choice of pancreatic progenitors between the endocrine and acinar cell lineage is restricted by cross-repressive interactions betwee...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Schaffer, Ashleigh E., Freude, Kristine K., Nelson, Shelley B., Sander, Maike
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133668/
https://ncbi.nlm.nih.gov/pubmed/20627083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.05.015
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !