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Mycobacterium tuberculosis-Specific CD8(+) T Cells Require Perforin to Kill Target Cells and Provide Protection In Vivo()

Optimal immunity to Mycobacterium tuberculosis (Mtb) infection requires CD8(+) T cells, and several current Mtb vaccine candidates are being engineered to elicit enhanced CD8(+) T cell responses. However, the function of these T cells and the mechanism by which they provide protection is still unkno...

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Autori principali: Woodworth, Joshua S., Wu, Ying, Behar, Samuel M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133658/
https://ncbi.nlm.nih.gov/pubmed/19050279
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