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Mycobacterium tuberculosis-Specific CD8(+) T Cells Require Perforin to Kill Target Cells and Provide Protection In Vivo()
Optimal immunity to Mycobacterium tuberculosis (Mtb) infection requires CD8(+) T cells, and several current Mtb vaccine candidates are being engineered to elicit enhanced CD8(+) T cell responses. However, the function of these T cells and the mechanism by which they provide protection is still unkno...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133658/ https://ncbi.nlm.nih.gov/pubmed/19050279 |
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