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Sequence- and structure-specific RNA processing by a CRISPR endonuclease

Many prokaryotes contain genomic clustered regularly interspaced short palindromic repeats (CRISPRs) that confer resistance to invasive genetic elements. Central to this immune system is the production of CRISPR-derived RNAs (crRNAs) following transcription of the CRISPR locus. Here we identify the...

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Bibliografiske detaljer
Main Authors: Haurwitz, Rachel E., Jinek, Martin, Wiedenheft, Blake, Zhou, Kaihong, Doudna, Jennifer A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133607/
https://ncbi.nlm.nih.gov/pubmed/20829488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1192272
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