THE IMMUNOPROTEASOME, THE 20S PROTEASOME, AND THE PA28αβ PROTEASOME REGULATOR ARE OXIDATIVE-STRESS-ADAPTIVE PROTEOLYTIC COMPLEXES

Oxidized cytoplasmic and nuclear proteins are normally degraded by proteasome, but accumulate with age and disease. We demonstrate the importance of various forms of the proteasome during transient (reversible) adaptation (hormesis), to oxidative stress in murine embryonic fibroblasts. Adaptation wa...

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Bibliografiske detaljer
Main Authors: Pickering, Andrew M., Koop, Alison L., Teoh, Cheryl Y., Ermak, Gennady, Grune, Tilman, Davies, Kelvin J. A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133595/
https://ncbi.nlm.nih.gov/pubmed/20919990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100878
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