Endotoxin-induced uveitis is primarily dependent on radiation-resistant cells and on MyD88 but not TRIF

TLR4 activation by LPS (endotoxin) is mediated by the MyD88 and TRIF intracellular signaling pathways. We determined the relative activation of these pathways in murine ocular tissue after LPS exposure. Additionally, we explored whether BM-derived or non-BM-derived cells were the major contributors...

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Bibliografiske detaljer
Main Authors: Kezic, J., Taylor, S., Gupta, S., Planck, S. R., Rosenzweig, H. L., Rosenbaum, J. T.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Leukocyte Biology 2011
Fag:
Receptors, Signal Transduction, & Genes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133435/
https://ncbi.nlm.nih.gov/pubmed/21610198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0111036
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