The Brd4 Extraterminal Domain Confers Transcription Activation Independent of pTEFb by Recruiting Multiple Proteins, Including NSD3

Bromodomain protein 4 (Brd4) plays critical roles in development, cancer progression, and virus-host pathogenesis. To gain mechanistic insight into the various biological functions of Brd4, we performed a proteomic analysis to identify and characterize Brd4-associated cellular proteins. We found tha...

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Autors principals: Rahman, Shaila, Sowa, Mathew E., Ottinger, Matthias, Smith, Jennifer A., Shi, Yang, Harper, J. Wade, Howley, Peter M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133372/
https://ncbi.nlm.nih.gov/pubmed/21555454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01341-10
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